About periCOVID 

This surveillance has been set up as part of Public Health England’s (PHE) response to the national outbreak of the novel coronavirus. It aims to answer important questions about the impact of the novel coronavirus on pregnant women and their infants, and the mode of transmission from mother to baby.

By collecting sequential samples from pregnant women with confirmed coronavirus disease and, after childbirth, from the newborn infant, we hope to better understand the risk and mode of perinatal transmission of the novel coronavirus in order to develop an evidence base for recommendations, guidance and policy decisions for the clinical and public health management of pregnant women, their infants and the healthcare staff that care for them.

Primary Objective

  • To assess the risk of COVID-19 infection in newborn infants born to pregnant women with confirmed COVID-19 infection and determine possible routes of mother-to-child transmission

 

Secondary Objectives

  • To genetically sequence SARS-CoV-2 samples

  • To test for SARS-CoV-2 in the pregnant woman

  • To test for SARS-CoV-2 in the placenta and cord blood at birth

  • To test for SARS-CoV-2 in newborn infants of women with confirmed COVID-19

  • To assess the immune responses to SARS-CoV-2 in pregnant women and their babies

  • To determine whether SARS-CoV-2 is found in breast milk

  • To determine whether SARS-CoV-2 is found in neonatal urine and faeces

  • To determine the duration of excretion of SARS-CoV-2 in all mother and baby samples

 

 

 

 

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Information for Healthcare Professionals